Intensity-Modulated Radiation Therapy (IMRT)

IMRT leverages advanced computer software to design and modulate radiation beams. It can be thought of as advanced "beam sculpting." 

IMRT uses detailed imaging information from computer software to create multiple small radiation beams. These beams can be shaped and adjusted to conform to the three-dimensional contours of the tumor. During treatment, the sculpted beams may move in an arc around the target area, delivering radiation from multiple angles.

Additionally, the intensity (strength) of the beams can also be adjusted. Higher intensity is delivered to the tumor itself, while lower intensity reaches surrounding healthy tissues.

Although traditional radiation uses radiation beams, they come in a more uniform shape. The precise targeting offered by IMRT means that higher radiation doses can be delivered directly to the tumor while also ensuring reduced radiation exposure to healthy tissues surrounding the tumor.

IMRT plays a valuable role in sarcoma treatment.

• Pre-Operative Therapy: IMRT can be used before surgery to shrink tumors. Reduction in tumor size means:
  • Less Invasive Surgery: Smaller tumors may allow for less-invasive surgical procedures, potentially reducing recovery time and pain.
  • Improved Surgical Outcomes: Precise targeting with IMRT may enhance the effectiveness of surgery by ensuring complete tumor removal.
  • Better Limb/Tissue Preservation: By shrinking tumors, IMRT may help preserve healthy limbs and tissues that might otherwise require removal during surgery.
• Reduced Recurrence Risk: IMRT's high precision allows for targeted treatment of cancer cells, potentially reducing the risk of cancer recurring after surgery.
• Treatment Near Critical Structures: Sarcomas can sometimes be located near vital structures like nerves or blood vessels. IMRT's exceptional precision minimizes radiation exposure to these healthy tissues, reducing the risk of potential side effects.

The treatment process with IMRT uses the following steps.

• Simulation and Planning: Similar to EBRT, IMRT involves simulation procedures using imaging techniques like CT scans. The information from an imaging test like a CT scan creates a precise map of the tumor and surrounding anatomy. IMRT specialists then use computer software to design the optimal beam shapes and dosage for your specific case.
• Treatment Sessions: IMRT treatment is typically delivered on an outpatient basis. Patients typically receive daily sessions (usually five days a week) for several weeks. However, each session is brief, lasting only a few minutes.

Potential side effects of IMRT can include:

• Fatigue
• Skin irritation in the treatment area (similar to a sunburn)
• Nausea
• Hair loss

These side effects are often temporary and manageable with medication and supportive care. Your doctor will discuss the potential side effects specific to your case and the measures available to manage them.

IMRT is not a one-size-fits-all treatment, and our team develops a personalized treatment plan based on factors such as:

• Type and stage of your sarcoma
• Size and location of the tumor
• Your overall health
• Your tolerance for potential side effects

IMRT is a powerful tool used to fight sarcoma. Understanding how it works and its potential benefits and risks can empower you to make informed decisions about your treatment plan.

At our office in Santa Monica, we design personalized and innovative plans for treating a wide variety of sarcomas. Our experienced oncologists can discuss your situation and help explore your treatment options.  

To schedule a consultation, please call us at 310-552-9999 or request an appointment online.